Summary
Overview
Work History
Education
Skills
Publications
Timeline
Generic

Stefan Stoiber

PhD Candidate
Vienna

Summary

Compassionate, diligent and trusty wetlab scientist with 7+ years of experience in the cultivation and analyses of immortalized and primary cells (2D and 3D culture) as well as in vivo cancer models in the field of solid tumors, such as prostate and head and neck cancer. Self-taught know-how in the application of data science and bioinformatics to independently answer biological questions in silico (mainly R). Strong experience in solving complex problems together with clinical, biological and computer science experts.

Overview

7
7
years of professional experience
10
10
years of post-secondary education

Work History

PhD Candidate

Medical University of Vienna, Department of Pathology
Vienna
2019.08 - Current
  • Established a pipeline for integrating data from multiple sources (imaging, genomic, and clinical) for various cancer types, including head and neck, prostate, breast, and lung cancer
  • Integrated in silico findings into in vitro / in vivo models
  • Supervised undergraduate and new PhD students, guiding them through their initial research steps
  • Demonstrated a passion for continuous learning and improvement
  • Cultivated strong interpersonal skills by building positive relationships with collaborators from various fields, leading to numerous projects and publications

Master Internship

University of Applied Sciences Technikum Vienna
Vienna
2018.04 - 2019.07
  • Cultivated murine cardiovascular progenitor cells (CVPCs) under stem cell conditions
  • Designed, fabricated, and characterized microfluidic devices
  • Developed a platform for spatially-defined cell characterization of a miniaturized heart tissue model, generated from CVPCs, using microfluidic devices

Bachelor Internship

University of Natural Resources Vienna
Vienna
2017.01 - 2018.05
  • Established an advanced 3D in vitro disease model of chordoma tumors using patient-derived bone scaffolds
  • Investigated the therapeutic effects of dimethylshikonin on chordoma tumors
  • Performed dynamic cultivation of chordoma cells to mimic physiological conditions.

Junior Researcher

University of Applied Sciences Technikum Vienna
Vienna
2017.10 - 2018.04
  • Tested novel techniques for the physiological 3D cultivation of human mesenchymal stem cells in collaboration with LifeTaq-Analytics GmbH

Education

Ph.D. - Cancer Research (UN094 Malignant Diseases)

Medical University of Vienna
Vienna
2019.08 - Current

Master of Science - Tissue Engineering And Regenerative Medicine

University of Applied Sciences Technikum Vienna
Vienna
2017.09 - 2019.07

Bachelor of Science - Biomedical Engineering

University of Applied Sciences Technikum Vienna
Vienna
2014.09 - 2017.07

Skills

    Cancer biology

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Publications

1: Stoiber S, Brkic FF, Maier T, Schnoell J, Gurnhofer E, Heiduschka G, Kadletz-
Wanke L, Kenner L. β-CATENIN is a positive prognostic marker for HPV-positive
head and neck squamous cell carcinoma. J Cancer Res Clin Oncol. 2023 Apr 3. doi:
10.1007/s00432-023-04712-3. Epub ahead of print. PMID: 37010585.

2: Varatanovic S, Maier T, Al-Gboore S, Stoiber S, Kandathil SA, Quint C,
Brennus C, Heiduschka G, Kadletz-Wanke L, Brkic FF. In vitro effects of gamma-
secretase inhibition in HPV-positive and HPV-negative head and neck squamous
cell carcinoma. Invest New Drugs. 2023 Apr;41(2):193-201. doi:
10.1007/s10637-023-01334-x. Epub 2023 Feb 21. PMID: 36809443; PMCID:
PMC10140088.

3: Brkic FF, Stoiber S, Al-Gboore S, Quint C, Schnoell J, Scheiflinger A,
Heiduschka G, Brunner M, Kadletz-Wanke L. Evaluation of the Prognostic Capacity
of a Novel Survival Marker in Patients with Sinonasal Squamous Cell Carcinoma.
Nutrients. 2022 Oct 17;14(20):4337. doi: 10.3390/nu14204337. PMID: 36297021;
PMCID: PMC9610224.

4: Spielvogel CP, Stoiber S, Papp L, Krajnc D, Grahovac M, Gurnhofer E,
Trachtova K, Bystry V, Leisser A, Jank B, Schnoell J, Kadletz L, Heiduschka G,
Beyer T, Hacker M, Kenner L, Haug AR. Radiogenomic markers enable risk
stratification and inference of mutational pathway states in head and neck
cancer. Eur J Nucl Med Mol Imaging. 2023 Jan;50(2):546-558. doi:
10.1007/s00259-022-05973-9. Epub 2022 Sep 26. PMID: 36161512; PMCID: PMC9816299.

5: Maier T, Stoiber S, Gurnhofer E, Haas M, Kenner L, Heiduschka G, Kadletz-
Wanke L, Brkic FF. Inhibition of beta-catenin shows therapeutic potential in
head and neck squamous cell carcinoma in vitro. Eur Arch Otorhinolaryngol. 2023
Jan;280(1):399-408. doi: 10.1007/s00405-022-07598-y. Epub 2022 Aug 24. PMID:
36001136; PMCID: PMC9813240.

6: Schnoell J, Jank BJ, Kadletz-Wanke L, Stoiber S, Gurnhofer E, Schlederer M,
Heiduschka G, Kenner L. Protein Expression of Folate Receptor Alpha in Adenoid
Cystic Carcinoma of the Head and Neck. Onco Targets Ther. 2022 May
16;15:531-538. doi: 10.2147/OTT.S351500. PMID: 35601979; PMCID: PMC9122665.

7: Brkic FF, Stoiber S, Maier T, Gurnhofer E, Kenner L, Heiduschka G, Kadletz-
Wanke L. Targeting Wnt/Beta-Catenin Signaling in HPV-Positive Head and Neck
Squamous Cell Carcinoma. Pharmaceuticals (Basel). 2022 Mar 20;15(3):378. doi:
10.3390/ph15030378. PMID: 35337176; PMCID: PMC8955953.

8: Friedl M, Stoiber S, Brkic FF, Kadletz-Wanke L. Pretherapeutic Serum Albumin
as an Outcome Prognosticator in Head and Neck Adenoid-Cystic Carcinoma.
Biomedicines. 2022 Jan 17;10(1):191. doi: 10.3390/biomedicines10010191. PMID:
35052870; PMCID: PMC8774260.

9: Schnoell J, Kotowski U, Jank BJ, Stoiber S, Gurnhofer E, Schlederer M,
Heiduschka G, Kenner L, Kadletz-Wanke L. Prognostic Relevance of Thyroid-
Hormone-Associated Proteins in Adenoid Cystic Carcinoma of the Head and Neck. J
Pers Med. 2021 Dec 12;11(12):1352. doi: 10.3390/jpm11121352. PMID: 34945824;
PMCID: PMC8703850.

10: Brkic FF, Stoiber S, Friedl M, Maier T, Heiduschka G, Kadletz-Wanke L. The
Potential Prognostic Value of a Novel Hematologic Marker Fibrinogen-to-
Lymphocyte Ratio in Head and Neck Adenoid-Cystic Carcinoma. J Pers Med. 2021 Nov
19;11(11):1228. doi: 10.3390/jpm11111228. PMID: 34834580; PMCID: PMC8620294.

11: Liang HC, Costanza M, Prutsch N, Zimmerman MW, Gurnhofer E, Montes-Mojarro
IA, Abraham BJ, Prokoph N, Stoiber S, Tangermann S, Lobello C, Oppelt J,
Anagnostopoulos I, Hielscher T, Pervez S, Klapper W, Zammarchi F, Silva DA,
Garcia KC, Baker D, Janz M, Schleussner N, Fend F, Pospíšilová Š, Janiková A,
Wallwitz J, Stoiber D, Simonitsch-Klupp I, Cerroni L, Pileri S, de Leval L,
Sibon D, Fataccioli V, Gaulard P, Assaf C, Knörr F, Damm-Welk C, Woessmann W,
Turner SD, Look AT, Mathas S, Kenner L, Merkel O. Super-enhancer-based
identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic
large cell lymphoma. Nat Commun. 2021 Sep 22;12(1):5577. doi:
10.1038/s41467-021-25379-9. PMID: 34552066; PMCID: PMC8458384.

12: Schnoell J, Jank BJ, Kadletz-Wanke L, Stoiber S, Spielvogel CP, Gurnhofer E,
Kenner L, Heiduschka G. Transcription factors CP2 and YY1 as prognostic markers
in head and neck squamous cell carcinoma: analysis of The Cancer Genome Atlas
and a second independent cohort. J Cancer Res Clin Oncol. 2021
Mar;147(3):755-765. doi: 10.1007/s00432-020-03482-6. Epub 2020 Dec 14. PMID:
33315124; PMCID: PMC7872999.


Timeline

PhD Candidate

Medical University of Vienna, Department of Pathology
2019.08 - Current

Ph.D. - Cancer Research (UN094 Malignant Diseases)

Medical University of Vienna
2019.08 - Current

Master Internship

University of Applied Sciences Technikum Vienna
2018.04 - 2019.07

Junior Researcher

University of Applied Sciences Technikum Vienna
2017.10 - 2018.04

Master of Science - Tissue Engineering And Regenerative Medicine

University of Applied Sciences Technikum Vienna
2017.09 - 2019.07

Bachelor Internship

University of Natural Resources Vienna
2017.01 - 2018.05

Bachelor of Science - Biomedical Engineering

University of Applied Sciences Technikum Vienna
2014.09 - 2017.07
Stefan StoiberPhD Candidate